CDK9-IN-8 is a highly effective and selective CDK9 inhibitor with an IC50 of 12 nM.

Product information

CAS Number: 2105956-51-0

Molecular Weight: 569.63

Formula: C31H32FN7O3

Chemical Name: N'1-(4-{[7-cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino}phenyl)-N1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide

Smiles: CN(C)C(=O)C1=CC2=CN=C(NC3C=CC(=CC=3)NC(=O)C3(CC3)C(=O)NC3C=CC(F)=CC=3)N=C2N1C1CCCC1

InChiKey: KXUNYNZTSOIXMY-UHFFFAOYSA-N

InChi: InChI=1S/C31H32FN7O3/c1-38(2)27(40)25-17-19-18-33-30(37-26(19)39(25)24-5-3-4-6-24)36-23-13-11-22(12-14-23)35-29(42)31(15-16-31)28(41)34-21-9-7-20(32)8-10-21/h7-14,17-18,24H,3-6,15-16H2,1-2H3,(H,34,41)(H,35,42)(H,33,36,37)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 5.2 mg/mL (9.13 mM; ultrasonic and warming and heat to 80°C). H2O : < 0.1 mg/mL (insoluble).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.